Adipogen
Butyrolactone I
Butyrolactone I
SKU: BVT-0448-C200
Brand: Adipogen
Lead Time: 2-3 weeks
Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor [1-4, 9, 10].
Apoptosis inducer [6, 7, 9].
Antitumor agent [5, 9].
Inhibits cell cycle progression at the G1/S and G2/M transitions [8].
Shown to prevent the phosphorylation of retinoblastoma protein and H1 histone [2, 10].
Important probe for understanding the cellular roles of CDKs [4].
Inhibitor of α-glucosidases [12].
Maturation inhibitor of sheep oocytes [11].
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General Specifications
1. Formula: C24H24O72. MW: 424.5
3. CAS: 87414-49-1
4. Source/Host Chemicals: Isolated from Aspergillus terreus.
5. Purity Chemicals: ≥98% (HPLC, NMR)
6. Appearance: White to off-white solid.
7. Solubility: Soluble in DMSO, methanol, ethanol or acetone.
8. Identity: Determined by 1H-NMR.
9. Shipping: AMBIENT
10. Short Term Storage: +4°C
11. Long Term Storage: -20°C
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