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Adipogen

AdipoRon

AdipoRon

SKU: AG-CR1-0154-M010
Brand: Adipogen
Lead Time: 2-3 weeks
  • Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low μm concentration [1, 2].
  • Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells [1].
  • Activates peroxisome proliferator-activated receptor γ coactivator 1-α (PGC1α) which boosts mitochondrial proliferation and energy metabolism [1].
  • Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms [1].
  • Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet [1].
  • Reduces expression levels of genes encoding inflammatory cytokines such as TNF-α, IL-6 and CCL-2 in WAT of WT mice but not db/db mice [1].
  • AdipoRon treatment elicits Antidepressant- and Anxiolytic-like effects
$454.00 SGD
$454.00 SGD
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Pack Size

General Specifications

1. Formula: C27H28N2O3
2. MW: 428.5
3. CAS: 924416-43-3
4. Purity Chemicals: ≥98% (NMR)
5. Appearance: White solid.
6. Solubility: Soluble in DMSO (~30mg/ml), 100% ethanol (~15mg/ml) or methanol (~10mg/ml). Insoluble in water.
7. Identity: Determined by 1H-NMR.
8. Shipping: AMBIENT
9. Short Term Storage: +4°C
10. Long Term Storage: -20°C

Safety & Documentation

MSDS
Data Sheet

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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.