Adipogen
Ganglioside GD1b . disodium salt
Ganglioside GD1b . disodium salt
Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD1b may act as a bacterial toxin receptor (tetanus, botulinus). High levels are found in gliomas and astrocytomas. It modulates protein kinase activities. In vivo and in vitro it is in equilibrium with the lactone structure.
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General Specifications
1. Formula: C84H146N4O39 . 2Na2. MW: 1836.1 . 46.0 (calculated on sphingosine C18:1 and stearic acid)
3. Sequence: Structure: II3Neu5Ac2GgOse4Cer; β-Gal-(1-3)-β-GalNAc-(1-4)-[α-Neu5Ac-(2-8)-α-Neu5Ac
-(2-3)-]β-Gal-(1-4)-β-Glc-(1-1)-Cer; Cer: Sphingosine C18:1-C20:1, ~1:1 to 1:3 by vol.; stearic acid over 90%
4. CAS: 19553-76-5
5. Source/Host Chemicals: Isolated from bovine brain.
6. Purity Chemicals: ≥98% (TLC)
7. Solubility: Soluble in water (micellar aggregates) or chloroform:methanol (2:1).
8. Formulation: Lyophilized.
9. Endotoxin Content: Not detectable.
10. Identity: Determined by 1H-NMR, MS and HPTLC.
11. Shipping: AMBIENT
12. Short Term Storage: +4°C
13. Long Term Storage: -20°C
Safety & Documentation
Error in entry: MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_AG_CN2_9004.pdf?v=1734335188, Manual Ganglioside GD1b . disodium salt (bovine brain), https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Manual_AG-CN2-9004-Ganglioside-GD1b-disodium-salt.pdf?v=1734398694
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.