Adipogen
Oligomycin A
Oligomycin A
Potent mitochondrial ATP synthase (ATPases (F0F1)) inhibitor, consequently leading to inhibition of oxidative phosphorylation (OXPHOS).
Useful agent for immunometabolism research. Inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production), significantly reducing electron flow through the electron transport chain.
Anticancer agent. Shown to induce apoptosis/necroptosis in a variety of cell types, as well as autophagy.
Shown to activate AMPK.
Broad antifungal, antibiotic and nematocidal agent.
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General Specifications
1. Formula: C45H74O112. MW: 791.1
3. CAS: 579-13-5
4. RTECS: RK3328000
5. Source/Host Chemicals: Originally isolated from Streptomyces diastatochromogenes.
6. Purity Chemicals: ≥95%
7. Appearance: White to off-white solid.
8. Solubility: Soluble in DMSO (20mg/ml), ethanol (20mg/ml) or DMF (20mg/ml).
9. Shipping: AMBIENT
10. Short Term Storage: +4°C
11. Long Term Storage: -20°C
Safety & Documentation
Error in entry: MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_AG_CN2_0517.pdf?v=1734335188, Manual Oligomycin A, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Manual_AG-CN2-0517-Oligomycin-A.pdf?v=1734398694
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.