Adipogen
Latrunculin A
Latrunculin A
Cell permeable marine toxin [1].
Disrupts microfilament-mediated processes [2].
Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin [1, 2, 3, 6].
Depolymerizes actin filaments (F-actin) [3].
Potent phagocytosis inhibitor [4].
Anticancer compound [7, 8]. Suppresses hypoxia-induced HIF-1 activation in tumor cells [7]. Inhibits tumor cell invasion [7].
Acts via a different mechanism than cytochalasins.
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General Specifications
1. Formula: C22H31NO5S2. MW: 421.6
3. Merck Index: 14: 5378
4. CAS: 76343-93-6
5. Source/Host Chemicals: Isolated from Latrunculia magnifica.
6. Purity Chemicals: ≥97% (HPLC)
7. Appearance: Colorless viscous film
8. Solubility: Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).
9. Identity: Determined by 1H-NMR.
10. Shipping: AMBIENT
11. Short Term Storage: +4°C
12. Long Term Storage: -20°C
Safety & Documentation
Error in entry: MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_AG_CN2_0027.pdf?v=1734335188, Manual Latrunculin A, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Manual_AG-CN2-0027-Latrunculin-A.pdf?v=1734398694
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.