Rapamycin

Antibiotic.
Antibacterial and antifungal properties [1, 2].
Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells [3, 5, 6, 11].
Potent immunosuppressant [4, 10] used as an alternative to calcineurin inhibitors [12].
Restricts the proliferation of smooth-muscle cells by blocking cell cycle progression at the G1/S transition [7, 13].
Anti-proliferative. Antitumor compound [14, 15].
Apoptosis enhancer. Activator of autophagy both in vitro and in vivo [8, 9].
Anti-HIV and anti-aging compound [16, 17].
Neuroprotective [18].
Suppressor for self-renewal and vascular differentiation potential in hemangioma stem cells [19].
mTORC1 inhibitor [20].