Adipogen
FasL (human) (multimeric) (rec.)
FasL (human) (multimeric) (rec.)
MultimericFasL™ is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively mimics the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
FasL treatment of stem cells is a robust method for proliferating cells in culture while improving their stemness properties. Treatment with FasL results in a large quantity of Adipose Derived Stem Cells (ASC) of high quality.
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General Specifications
1. Source/Host: HEK 293 cells2. Sequence: Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
3. Specificity: Binds to human and mouse Fas.
4. Biological Activity: Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
5. MW: ~40kDa (SDS-PAGE)
6. Purity: ≥95% (SDS-PAGE)
7. Endotoxin Content: <0.02EU/μg purified protein (LAL test).
8. Concentration: 0.1mg/ml after reconstitution.
9. Reconstitution: Reconstitute with 100μl sterile water.
10. Formulation: Lyophilized. Contains PBS.
11. Shipping: BLUE ICE
12. Short Term Storage: +4°C
13. Long Term Storage: -20°C
Safety & Documentation
Error in entry: MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_AG_40B_0130.pdf?v=1734335188, Manual FasL (human) (multimeric) (rec.), https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Manual_AG-40B-0130-FasL-human-multimeric-rec.pdf?v=1734398694
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.