Adipogen
anti-ZBP1, mAb (Zippy-1)
anti-ZBP1, mAb (Zippy-1)
ZBP1 is an interferon inducible protein that binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. ZBP1 is an innate immune sensor of Influenza A virus (IAV). ZBP1 regulates NLRP3 (nucleotide and oligomerization domain, leucine-rich repeat-containing protein family, pyrin domain containing 3) inflammasome activation as well as induction of different types of cell death (apoptosis, necroptosis and pyroptosis) during IAV infection.
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General Specifications
1. Clone: Zippy-12. Isotype: Mouse IgG2a
3. Source/Host: Purified from concentrated hybridoma tissue culture supernatant.
4. Immunogen/Antigen: Recombinant mouse ZBP1 (aa 1-411).
5. Specificity: Recognizes human and mouse ZBP1.
6. Purity: ?95% (SDS-PAGE)
7.Purity Detail: Protein G-affinity purified.
8.Concentration: 1mg/ml
9. Formulation: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
10. Shipping: BLUE ICE
11. Short Term Storage: +4°C
12. Long Term Storage: -20°C
Safety & Documentation
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.