Adipogen
DLK1 (human) (rec.)
DLK1 (human) (rec.)
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-? converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
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General Specifications
1. Source/Host: HEK 293 cells2. Sequence: Signal peptide and extracellular domain of human DLK1 (aa 1-303) are fused at the C-terminus to a FLAG®-tag.
3. MW: ~40kDa (SDS-PAGE)
4. Purity: ?90% (SDS-PAGE)
5. Endotoxin Content: <0.1EU/?g purified protein (LAL test; Lonza).
6. Formulation: Lyophilized. Contains PBS.
7. Shipping: BLUE ICE
8. Short Term Storage: +4°C
9. Long Term Storage: -20°C
Safety & Documentation
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only and are not intended for human use. We do not sell to patients.