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Adipogen

BCMA (mouse):Fc (human) (rec.)

BCMA (mouse):Fc (human) (rec.)

SKU: AG-40B-0076-C050
Brand: Adipogen
Lead Time: 2-3 weeks

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-κB and JNK.

Regular price $821.00 SGD
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General Specifications

1.Synonyms: B Cell Maturation Protein; CD269; TNFRSF17
2.Product Type: Protein
3.Source/Host: HEK 293 cells
4.Sequence: The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.
5.Crossreactivity:
Human
Mouse
6.Specificity: Binds mouse and human BAFF and APRIL.
7.Biological Activity: Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.
8.MW: ~35kDa (SDS-PAGE)
9.Purity: ≥95% (SDS-PAGE)
10.Endotoxin Content: <0.01EU/μg purified protein (LAL test; Lonza).
11.Concentration: 1mg/ml after reconstitution.
12.Reconstitution: Reconstitute with 50μl sterile water.
13.Formulation: Lyophilized. Contains PBS.
14.Protein Negative Control
Fc (human) IgG1 Control (rec.)
15.Other Product Data:
UniProt link O88472: BCMA (mouse)
16.Shipping: BLUE ICE
17.Short Term Storage: +4°C
18.Long Term Storage: -20°C
19.Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
20.Use/Stability:
Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.

Safety & Documentation

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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.