Adipogen
Momelotinib
Momelotinib
CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) < 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCµ), ROCK2, and TBK1 kinase as well.
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General Specifications
1. Formula: C23H22N6O22. MW: 414.5
3. Purity Chemicals: ≥95%
4. Appearance: Solid.
5. Solubility: Soluble in DMSO.
6. Declaration: Manufactured by SynKinase.
7. Shipping: AMBIENT
8. Short Term Storage: +4°C
9. Long Term Storage: -20°C
Safety & Documentation
Error in entry: MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_SYN_1035.pdf?v=1734335190, Manual Momelotinib, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Manual_SYN-1035-Momelotinib.pdf?v=1734398695
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.