Adipogen
anti-BAFF (mouse), mAb (blocking) (Sandy-2)
anti-BAFF (mouse), mAb (blocking) (Sandy-2)
BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
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General Specifications
1. Clone: Sandy-22. Isotype: Mouse IgG1κ
3. Source/Host: Purified from concentrated hybridoma tissue culture supernatant.
4. Immunogen/Antigen: Recombinant mouse BAFF.
5.Specificity: Recognizes mouse BAFF.
6. Purity: ≥95% (SDS-PAGE)
7. Purity Detail: Protein G-affinity purified.
8. Endotoxin Content: <0.01EU/μg purified protein (LAL test).
9. Concentration: 1mg/ml
10. Formulation: Liquid. In PBS containing 0.02% sodium azide.
11. Shipping: BLUE ICE
12. Short Term Storage: +4°C
13. Long Term Storage: +4°C
Safety & Documentation
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.