Adipogen
anti-Caspase-1 (p20) (human), mAb (Bally-1)
anti-Caspase-1 (p20) (human), mAb (Bally-1)
SKU: AG-20B-0048-C100
Brand: Adipogen
Lead Time: 2-3 weeks
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1? (IL-1?) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
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General Specifications
1. Clone: Bally-12. Isotype: Mouse IgG1
3. Source/Host: Purified from concentrated hybridoma tissue culture supernatant.
4. Immunogen/Antigen: Recombinant human caspase-1.
5. Specificity: Recognizes endogenous full-length and activated (p20 fragment) human caspase-1.
6. Purity: ?95% (SDS-PAGE)
7. Purity Detail: Protein G-affinity purified.
8. Concentration: 1mg/ml
9. Formulation: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
10. Shipping: BLUE ICE
11. Short Term Storage: +4°C
12. Long Term Storage: -20°C
Safety & Documentation
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.