MCE
Pexidartinib
Pexidartinib
SKU: HY-16749
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity.
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General Specifications
1) Purity: 99.64%2) Molecular Weight: 417.81
3) Formula: C20H15ClF3N5
4) CAS No.: 1029044-16-3
5) Appearance: Solid
6) Color: Off-white to light yellow
7) SMILE: FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=N1)(F)F
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 1 year ; -20°C, 6 months
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only and are not intended for human use. We do not sell to patients.