MCE
Cilengitide
Cilengitide
SKU: HY-16141
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Cilengitide (EMD 121974) is a potent integrins antagonist with IC50s of 0.61 nM (ανβ3), 8.4 nM (ανβ5) and 14.9 nM (α5β1), respectively. Cilengitide inhibits the binding of ανβ3 and ανβ5 to Vitronectin with IC50s of 4 nM and 79 nM, respectively. Cilengitide inhibits TGF-β/Smad signaling, mediates PD-L1 expression. Cilengitide also induces apoptosis, shows antiangiogenic effect in the research against glioblastoma and other cancers.
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$370.00 SGD
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General Specifications
1) Purity: 99.80%2) Molecular Weight: 588.66
3) Formula: C27H40N8O7
4) CAS No.: 188968-51-6
5) Appearance: Solid
6) Color: White to light yellow
7) SMILE: O=C(NCC(N[C@H](C(N[C@H](CC1=CC=CC=C1)C(N([C@H]2C(C)C)C)=O)=O)CC(O)=O)=O)[C@H](CCCNC(N)=N)NC2=O
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; In solvent: -80°C, 1 year ; -20°C, 6 months
Safety & Documentation
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.