MCE
SB-431542
SB-431542
SKU: HY-10431
Brand: MedChemExpress
Lead Time: 1-2 Weeks
SB-431542 is a TGF-β receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways.
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General Specifications
1) Purity: 99.85%2) Molecular Weight: 384.39
3) Formula: C22H16N4O3
4) CAS No.: 301836-41-9
5) Appearance: Solid
6) Color: Off-white to yellow
7) SMILE: O=C(C1=CC=C(C=C1)C2=NC(C3=CC=C4OCOC4=C3)=C(N2)C5=NC=CC=C5)N
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 2 years ; -20°C, 1 year
Safety & Documentation
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.