MCE
SN-38
SN-38
SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254).
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General Specifications
1) Purity: 99.89%2) Molecular Weight: 392.40
3) Formula: C22H20N2O5
4) CAS No.: 86639-52-3
5) Appearance: Solid
6) Color: Off-white to yellow
7) SMILE: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC(O)=CC=C5N=C4C3=C2)=O
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 1 year ; -20°C, 6 months
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-13704.pdf?v=1734506157 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-13704.pdf?v=1734506830 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-13704.pdf?v=1734506811
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.