MCE
Resatorvid
Resatorvid
Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases.
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General Specifications
1) Purity: 99.95%2) Molecular Weight: 361.82
3) Formula: C15H17ClFNO4S
4) CAS No.: 243984-11-4
5) Appearance: Solid
6) Color: Off-white to yellow
7) SMILE: O=S([C@H]1C(C(OCC)=O)=CCCC1)(NC2=CC=C(C=C2Cl)F)=O
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 6 months ; -20°C, 1 month
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-11109.pdf?v=1734506156 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-11109.pdf?v=1734506829 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-11109.pdf?v=1734506810
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.