MCE
BX795
BX795
BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKε, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy.
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General Specifications
1) Purity: 99.84%2) Molecular Weight: 591.47
3) Formula: C23H26IN7O2S
4) CAS No.: 702675-74-9
5) Appearance: Solid
6) Color: White to light brown
7) SMILE: O=C(NCCCNC1=C(C=NC(NC2=CC=CC(NC(N3CCCC3)=O)=C2)=N1)I)C4=CC=CS4
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 6 months ; -20°C, 1 month
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-10514.pdf?v=1734506156 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-10514.pdf?v=1734506829 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-10514.pdf?v=1734506808
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.