MCE
Dasatinib
Dasatinib
Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib also induces apoptosis and autophagy.
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General Specifications
1) Purity: 99.88%2) Molecular Weight: 488.01
3) Formula: C22H26ClN7O2S
4) CAS No.: 302962-49-8
5) Appearance: Solid
6) Color: White to off-white
7) SMILE: O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 2 years ; -20°C, 1 year
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-10181.pdf?v=1734506157 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-10181.pdf?v=1734506828 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-10181.pdf?v=1734506804
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.