MCE
Itraconazole
Itraconazole
SKU: HY-17514
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.
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General Specifications
1) Purity: 99.59%2) Molecular Weight: 705.63
3) Formula: C35H38Cl2N8O4
4) CAS No.: 84625-61-6
5) Appearance: Solid
6) Color: White to off-white
7) SMILE: ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: 4°C, protect from light ; In solvent: -80°C, 6 months ; -20°C, 1 month (protect from light)
Safety & Documentation
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only and are not intended for human use. We do not sell to patients.