MCE
Bafilomycin A1
Bafilomycin A1
Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis.
Couldn't load pickup availability
General Specifications
1) Purity: 99.95%2) Molecular Weight: 622.83
3) Formula: C35H58O9
4) CAS No.: 88899-55-2
5) Appearance: Solid
6) Color: White to light yellow
7) SMILE: C[C@H]([C@](O[C@@H]1C(C)C)(C[C@@H](O)[C@@H]1C)O)[C@H](O)[C@@H]([C@](OC(/C(OC)=C/C(C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C2)=O)([H])[C@H](/C=C/C=C2\C)OC)C
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: -20°C, protect from light ; In solvent: -80°C, 6 months ; -20°C, 1 month (protect from light)
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-100558.pdf?v=1734506156 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-100558.pdf?v=1734506830 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-100558.pdf?v=1734506812
{# This line will help debug any improperly formatted entries #}
Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.