MCE
Sotorasib
Sotorasib
Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors.
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General Specifications
1) Purity: 99.94%2) Molecular Weight: 560.59
3) Formula: C30H30F2N6O3
4) CAS No.: 2296729-00-3
5) Appearance: Solid
6) Color: White to yellow
7) SMILE: O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: -20°C, stored under nitrogen ; In solvent: -80°C, 6 months ; -20°C, 1 month (stored under nitrogen)
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-114277.pdf?v=1734506157 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-114277.pdf?v=1734506830 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-114277.pdf?v=1734506812
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.