MCE
Doramapimod
Doramapimod
SKU: HY-10320
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38α=38 nM, for p38β=65 nM, for p38γ=200 nM, and for p38δ=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM.
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General Specifications
1) Purity: 99.98%2) Molecular Weight: 527.66
3) Formula: C31H37N5O3
4) CAS No.: 285983-48-4
5) Appearance: Solid
6) Color: Off-white to gray
7) SMILE: O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 1 year ; -20°C, 6 months
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.