MCE
Tamoxifen
Tamoxifen
Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse.
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General Specifications
1) Purity: 99.92%2) Molecular Weight: 371.51
3) Formula: C26H29NO
4) CAS No.: 10540-29-1
5) Appearance: Solid
6) Color: White to off-white
7) SMILE: CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(C=C3)OCCN(C)C
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: 4°C, protect from light ; In solvent: -80°C, 6 months ; -20°C, 1 month (protect from light)
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-13757A.pdf?v=1734506157 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-13757A.pdf?v=1734506831 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-13757A.pdf?v=1734506811
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.