MCE
PD98059
PD98059
PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy.
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General Specifications
1) Purity: 99.96%2) Molecular Weight: 267.28
3) Formula: C16H13NO3
4) CAS No.: 167869-21-8
5) Appearance: Solid
6) Color: Light yellow to yellow
7) SMILE: O=C1C=C(OC2=CC=CC=C21)C3=CC=CC(OC)=C3N
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: 4°C, protect from light ; In solvent: -80°C, 1 year ; -20°C, 6 months (protect from light)
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-12028.pdf?v=1734506157 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-12028.pdf?v=1734506829 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-12028.pdf?v=1734506810
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.