MCE
A 83-01
A 83-01
A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.
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General Specifications
1) Purity: 99.41%2) Molecular Weight: 421.52
3) Formula: C25H19N5S
4) CAS No.: 909910-43-6
5) Appearance: Solid
6) Color: Off-white to light yellow
7) SMILE: S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: -20°C, protect from light, stored under nitrogen ; The compound is unstable in solutions, freshly prepared is recommended.
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-10432.pdf?v=1734506156 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-10432.pdf?v=1734506828 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-10432.pdf?v=1734506805
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.