MCE
Adezmapimod
Adezmapimod
SKU: HY-10256
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits LCK, GSK3β and PKBα with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod does not disrupt JNK activity and is an autophagy and mitophagy activator.
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General Specifications
1) Purity: 99.96%2) Molecular Weight: 377.43
3) Formula: C21H16FN3OS
4) CAS No.: 152121-47-6
5) Appearance: Solid
6) Color: White to light yellow
7) SMILE: O=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)C
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: Powder: -20°C, 3 years ; 4°C, 2 years ; In solvent: -80°C, 2 years ; -20°C, 1 year
Safety & Documentation
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only and are not intended for human use. We do not sell to patients.