MCE
Y-27632
Y-27632
SKU: HY-10071
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Y-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation.
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General Specifications
1) Purity: 99.91%2) Molecular Weight: 247.34
3) Formula: C14H21N3O
4) CAS No.: 146986-50-7
5) Appearance: Solid
6) Color: White to off-white
7) SMILE: O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: -20°C, protect from light, stored under nitrogen ; In solvent: -80°C, 6 months ; -20°C, 1 month (protect from light, stored under nitrogen)
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only and are not intended for human use. We do not sell to patients.