MCE
RSL3
RSL3
RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.
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General Specifications
1) Purity: 99.90%2) Molecular Weight: 440.88
3) Formula: C23H21ClN2O5
4) CAS No.: 1219810-16-8
5) Appearance: Solid
6) Color: White to off-white
7) SMILE: O=C([C@H]1CC2=C([C@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: 4°C, sealed storage, away from moisture ; In solvent: -80°C, 2 years ; -20°C, 1 year (sealed storage, away from moisture)
Safety & Documentation
Error in entry: 1) Datasheet, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Datasheet_HY-100218A.pdf?v=1734506157 , 2) MSDS, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/MSDS_HY-100218A.pdf?v=1734506830 , 3) Handling Instruction, https://cdn.shopify.com/s/files/1/0716/2553/9802/files/Handling_Instructions_HY-100218A.pdf?v=1734506812
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.