MCE
Monomethyl auristatin E
Monomethyl auristatin E
SKU: HY-15162
Brand: MedChemExpress
Lead Time: 1-2 Weeks
Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.
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General Specifications
1) Purity: 99.97%2) Molecular Weight: 717.98
3) Formula: C39H67N5O7
4) CAS No.: 474645-27-7
5) Appearance: Solid
6) Color: White to yellow
7) SMILE: CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@@H](CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O
8) Shipping: Room temperature in continental US; may vary elsewhere.
9) Storage: -20°C, sealed storage, away from moisture and light ; The compound is unstable in solutions, freshly prepared is recommended.
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Disclaimer: Products are chemical reagents for research use
only and are not intended for human use. We do not sell to patients.